- Issue Time
Hyaluronic acid is an acidic mucopolysaccharide found in all tissues and fluids of the body, a large part of which is located in the dermis of the human skin, where it acts as an intercellular filler and is one of the most abundant substrates in the dermis, which is the reason why the dermis provides constant moisture to the epidermis.
After entering the dermis, hyaluronic acid hydrates with the cells and is gradually absorbed and metabolised by the body as time passes. In general, hyaluronic acid lasts between 6 and 18 months. This is positively correlated with the degree of cross-linking of hyaluronic acid. The greater the degree of cross-linking, the slower the degradation of hyaluronic acid, the longer it will last, and the larger the particles of hyaluronic acid, the longer it will last.
The absorption of hyaluronic acid then varies depending on our rate of metabolism. The metabolism is also affected by our personal constitution and lifestyle habits. Generally speaking, staying up late and drinking alcohol will affect our metabolism, and hyaluronic acid absorption may be faster for people who stay up late and drink a lot.
The amount and depth of hyaluronic acid injections, the location of the injections, and the skill of the doctor will also affect the maintenance time.